Fatty compound of iodin and sulfur and process of making same.



UNITED STATES PATENT OFFICE.

OTTO DEGNER, OF ELBERFELD, GERMANY, ASSIGNOR TO FARBENFABRI- KEN OFELBERFELD 00., OF NElV YORK, N. Y., A CORPORATION OF NEYV YORK.

FATTY COMPOUND OF lODlll AND SULFUR AND PROCESS OF MAKING SAME.

slEGIFlCATION mrmjngpart of Letters Patent No. 696,900, dated April 1, 1902 Application filed December 21, 1901. Serial No- 86,828. (Specimens)T at whom it may concern.-

Be it known that I, OTTO DEGNEB, doctor of philosophy, chemist, residingat Elberfeld, Germany, (assignor to the FARBENFABRIKEN or ELBERFELD 00.,of New York,) have invented a new and useful Improvement in'a FattyOompound of Iodin and Sulfur and Process of Making the Same, of whichthe following is a specification.

1o Fats containing in their molecule sulfur and iodin have not beenknown up to this day. I have now succeeded in finding a process forpreparing such bodies. This process consists in at first treating withiodin and hy- I5 drogen sulfid fats, such as sesame-oil, poppyoil,olive-oil, bacon-fat, oleic acid, or the like; secondly, purifying thereaction mass, and, thirdly, isolating the resulting new bodies. I pointout distinctly that under the name fats I mean fats, fatty oils,unsaturated fatty acids, or the like.

The new bodies obtainable by means of my new process are oily liquidsmore or less colored which are soluble in benzene, ether, and

ligroin. They do not split off iodin on being heated on the water-bathand can be kept long without decomposition. Owing to the fact that iodinand sulfur are intimately combined with the fatty molecule, they exhibitno irritating action on the mucous membranes. Nevertheless the valuableaction of iodin and sulfur therein is not diminished. For this reasonthe new compounds can profitably be used in medicine, an average dosebeing from two to five grams, according to the percentage of iodin andsulfur contained therein.

In carrying out my new process practically I can proceed as follows, theparts being by weight: Twenty-five parts of iodin are in- 0troducedintoasolutionoffiftypartsofsesameoil in fifty parts of benzene.Into the resulting mixture hydrogen sulfid is introduced u ntil aclearand colorless solution results. By repeated washing with water andalcohol the 5 reaction mass is freed from an excess of hydrogen sulfidand iodin. The solution is then gently heated 'in cacao in order toremove the benzene still contained therein. The resulting new bodyrepresents a yellowishbrown oil containing about thirty per cent. ofiodin and three per cent. of sulfur. It is soluble in ether, benzene,and ligroin. with a yellowish color. The iodin and sulfur containedtherein are so intimately combined with the molecule that they cannot bediscovered by. means of the usual agents. On heating the new body over afree flame it is decomposed, violet vapors of iodin being disengaged. Itcan be used in medicine either directly or diluted with sesame-oil orthe like.

The process proceeds in an analogous manner if others of theabove-mentioned fatty compounds be used.

On employing other proportions of iodin and hydrogen sulfid bodiescontaining an- 6 other percentage of iodin and sulfur can be obtained.

Having now described my invention and in what manner the same is to beperformed, what I claim as new, and desire to secure by Letters Patent,is

1. The process for producing new derivatives of fats containingsulfurand iodin,which process consists in at first treating fats with iodinand hydrogen sulfid, secondly purifying the reaction mass andthirdlyisolatinzg the new compounds,substantiallyas hereinbeforedescribed.

2. The process for producing a new derivative of sesame-oil containingiodin and sul- 8o fur, which process consists in at first treatingsesame-oil with iodin and hydrogen sulfid, sec ondly purifying thereaction mass and thirdly isolating the new compound, substantially ashereinbefore described.

3. The herein-described new derivatives of fats containing in themolecule iodin and sulfur being more orless colored oily liquids solublein benzene, ether and ligroin which do not split off iodin when heatedon the water-bath and being valuable remedies, substantially asdescribed.

4. The herein-described specific derivative of sesame-oil containingiodin and sulfur being a yellowish-brown oil soluble in benzene, etherand ligroin with a yellowish color, iodin and sulfur being so intimatelycombined In testimony whereof I have signed my therein with the moleculethat they cannot name in the presence of two subscribing witbediscovered by means of the usual agents, nesses.

being decomposed when heated over a free OTTO DEGNER. 5 flame Withdisengagement 0f violet vapors of Witnesses:

iodin and representing a valuable remedy, OTTO KONIG,

substantially as hereinbefore described. '1. A. RITTERSHAUS.

